Cyclosporin A: tissue levels following topical and systemic administration to rabbits.
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چکیده
منابع مشابه
Cyclosporin A: tissue levels following topical and systemic administration to rabbits.
Plasma and aqueous levels of cyclosporin A (CsA) were determined following topical administration of CsA 1% to healthy rabbit eyes and compared with levels obtained when administered to rabbit eyes which had received corneal grafts 7-10 days previously. In addition plasma levels were determined following intramuscular administration of 50 mg CsA and the results compared with those obtained foll...
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Cyclosporin A (CS-A), selectively inhibited cellular immunity, delayed the skin graft-induced rejection of corneal allografts in rabbits when administered subconjunctivally in the dose of 3 mg/kg/day or in the form of 5% water-soluble drops five times daily for 28 days. The subconjunctival application of CS-A was irritating, whereas the topical instillation of the water-soluble preparation was ...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 1986
ISSN: 0007-1161
DOI: 10.1136/bjo.70.11.852